Archive for the ‘Fosamax and Bisphosphonates’ Category

Fosamax and Bisphosphonates


Fosamax is a drug that helps reverse bone loss and bone thinning and prevents the onslaught of osteoporosis. Fosamax is also know as a bisphosphonate.

Over 10 million people suffer from osteoporosis, with over 34 million suffering from low bone mass. It is a difficult disease to self diagnose with a bone density test being used to determine it existence.

Fosamax and other stronger forms of bisphosphonates are often used to manage advanced cancers that have metastasized to the bone. In these cases the bisphosphonates are usually given intravenously for longer time periods.

Fosamax (alendronate sodium) is an aminobisphosphonate that acts as a specific inhibitor of osteoclast-mediated bone resorption. Bisphosphonates are synthetic analogs of pyrophosphate that bind to the hydroxyapatite found in bone.

Severe side effects have been linked to the use of bisphosphonates including Fosamax. These include osteonecrosis of the jaw (ONJ or ‘dead jaw’). Osteonecrosis of the jaw is a rare but serious condition that involves the loss, or breakdown, of the jaw bone. Symptoms include gum problems, loose teeth and heaviness of the jaw. The diagnosis of osteonecrosis is done by x-rays and microbial cultures. Treatments include antibiotics, rinses and removable mouth appliances.

Litigation and class actions are being brought about regarding complications from bisphosphonate relating to osteonecrosis of the jaw and other serve side effects.


Fosamax is a medication created to help osteoporosis, a bone disease which generally affects postmenopausal women in the United States. Fosamax is used by both men and women to treat the disease. It can be taken orally in either a pill or fluid format, and is generally consumed on an empty stomach.

The drug is used in aid of rebuilding and fortifying weak bones so that the person can avoid debilitating and harmful fractures of the bones. This little tablet helps control Paget’s disease and osteoporosis, but unfortunately it cannot prevent or cure them.

It’s unfortunate, but medication like Fosamax can cause serious complications for its users. Just like other osteoporosis dugs, Fosamax will cause severe gastrointestinal problems such as nausea and constipation. In rare instances, Fosamax can even result in Osteonecrosis of the jaw (or ‘dead jaw’) and harm one’s ability to eat, swallow and speak.

The pharmaceutical industry has developed and marketed numerous amounts of medications to prevent and treat these conditions, but unfortunately all of these drugs have severe side effects. Because the medications alter basic bodily functions so dramatically, the consequences of taking these medications can be sometimes be awful. Additional side effects can often include sleeplessness, nausea and fatigue.

If you or a loved one has been harmed by the use of osteoporosis medication such as Fosamax then you have the right to seek compensation for your injuries. It’s important that you call an experienced and knowledgeable osteoporosis drug attorney today.


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